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Searching for: cell proliferation

  • Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

    Sanjit K Roy, Rakesh K Srivastava, Sharmila Shankar

    • Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cells

      Shingo Tanaka, Kumiko Terada, Tsutomu Nohno

      • Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα12/13-Rho-Rac1 pathway

        Jing Li, Bin Guo, Jing Wang, Xiaoyan Cheng, Yan Xu, Jianli Sang

        • PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines

          Jianwen Que, Qizhou Lian, Reida M El Oakley, Bing Lim, Sai- Kiang Lim

          • Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression

            David C New, Yung H Wong

            • Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1

              Yongxian Zhuang, W Keith Miskimins

              • The metastasis suppressor Nm23 as a modulator of Ras/ERK signaling

                Krisztina Takács-Vellai

                • Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activities

                  Janani Panneerselvam, Anupama Munshi, Rajagopal Ramesh

                  • Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis

                    Sajad A War, Ujendra Kumar

                    • EGFR/Met association regulates EGFR TKI resistance in breast cancer

                      Kelly L Mueller, Zeng-Quan Yang, Ramsi Haddad, Stephen P Ethier, Julie L Boerner

                      • Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells

                        Vanessa González-Pérez, David J Reiner, Jamie K Alan, Cicely Mitchell, Lloyd J Edwards, Vladimir Khazak, Channing J Der, Adrienne D Cox

                        • Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation

                          Leonie von Elsner, Sandra Hagemann, Ingo Just, Astrid Rohrbeck

                          • Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Gαi, Gαq and Rho-dependent signaling pathways

                            Anurag Singh, José L Boyer, Channing J Der, Irene E Zohn

                            • Retinoic acid decreases ATF-2 phosphorylation and sensitizes melanoma cells to taxol-mediated growth inhibition

                              Ying Huang, Jennifer Minigh, Sarah Miles, Richard M Niles

                              • Peroxisome proliferator-activated receptor gamma ligand-mediated apoptosis of hepatocellular carcinoma cells depends upon modulation of PI3Kinase pathway independent of Akt

                                Prajna Mishra, Suresh K Paramasivam, Ramesh P Thylur, Ajay Rana, Basabi Rana

                                • Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cells

                                  Prajna Mishra, Subramanian Senthivinayagam, Ajay Rana, Basabi Rana

                                  • Signaling in colon cancer stem cells

                                    Sanchita Roy, Adhip P N Majumdar

                                    • Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and −8, and matrix metalloproteinase-2

                                      Crystal Y Chia, Udhaya Kumari, Patrick J Casey

                                      • “Shaping” of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor

                                        Salih S Koçer, Hsien-yu Wang, Craig C Malbon

                                        • A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1

                                          Yan Jiang, Vineshkumar T Puliyappadamba, Liyue Zhang, Wenjuan Wu, Anil Wali, Michael B Yaffe, Joseph A Fontana, Arun K Rishi

                                          • Identification of endoglin-dependent BMP-2- induced genes in the murine periodontal ligament cell line PDL-L2

                                            Osamu Ishibashi, Takashi Inui

                                            • The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition

                                              Su-Ni Tang, Chandan Singh, Dara Nall, Daniel Meeker, Sharmila Shankar, Rakesh K Srivastava

                                              • Expression analyses of nuclear receptor genes in breast cancer cell lines exposed to soy phytoestrogens after BRCA2 knockdown by TaqMan Low-Density Array (TLDA)

                                                Samir Satih, Hélène Savinel, Nadège Rabiau, Luc Fontana, Yves- Jean Bignon, Dominique J Bernard-Gallon

                                                • NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner

                                                  Eswar Shankar, Chandreyi Basu, Brett Adkins, Wolfram Siede, Alakananda Basu

                                                  • siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration

                                                    Douglas McHugh, James Wager-Miller, Jeremy Page, Heather B Bradshaw